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Urothel | IHC quantification | PD-L1

0-click solution to detect and quantify PD-L1 in urothelial carcinoma

Mindpeak Urothel PD-L1 is a standalone software module for the automated image analysis of digital histopathology images of scanned, fixed, and PD-L1-stained human urothelial cancer tissue samples.

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Mindpeak Urothel PD-L1 is intended for Research Use Only, not for use in diagnostic procedures.

Detailed information on Mindpeak Urothel PD-L1

Output

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Image analysis involves detecting and classifying IHC-stained tumor cells within whole slide images. Tumor cells are categorized as either unstained (tumor negative) or stained (tumor positive).

A corresponding tumor proportion score (TPS) is provided as the proportion of positive tumor cells among tumor cells, which is the number of positive tumor cells divided by the number of all tumor cells (i.e., the sum of tumor positive and tumor negative cells).

Workflow

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Step 1: Retrieve or select an image with the immunohistochemical PD-L1 staining, suited for diagnosis and automated analysis.

Step 2: The result of Mindpeak Urothel PD-L1 whole slide analysis is displayed.

Step 3: Review, adjust and correct the results of the automated analysis in an integrated interactive viewer module.

Step 4: Conclude a final diagnostic decision.

Required Software

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Mindpeak Urothel PD-L1 is a stand-alone software module for automated image analysis.

For interaction with the medical device, it must be integrated into an interactive image viewer software that allows the user to manually select or correct regions of interest for analysis with the medical device.

Required Hardware

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Mindpeak Urothel PD-L1 runs as a web service either in the cloud or on a dedicated on-premise server in the laboratory network. The cloud variant is specified and provided by Mindpeak or distribution partners and requires no additional hardware by the user. For minimum requirements for an on-premise solution, please contact us.

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Detection and quantification of urothel cancer cells

Identification & Quantification

Mindpeak Urothel PD-L1 detects and classifies cells into positively stained tumor and unstained tumor cells. One of its key advantages is its ability to distinguish between tumorous and non-tumorous structures, enhancing the accuracy of scoring within the tumor microenvironment. This capability ensures more reliable and precise assessments of PD-L1 expression, supporting your diagnostic decision-making.

0-Click

Image pre-calculation in the background allows instant visualization of all detected and classified cells. Just load the digital slide and you are done!

Lab Independent

The reliability of Mindpeak Urothel PD-L1 is unique: it provides accurate results even in challenging contexts, as it was developed with typical lab-specific variations in mind, such as slide preparation, staining and imaging.

Easy Integration

Mindpeak Urothel PD-L1 supports a broad range of scanners and can be seamlessly integrated into existing workflows.

Find out how Urothel PD-L1 can work for you

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